2023-11-24T11:30:33+08:002019-12-04|
Contact Information
Teaching
Education
Ph.D. Molecular Biology and Biochemistry,
Rutgers University, USA
M.S. Plant Genetics and Breeding,
Beijing Agricultural University, China
B.S. Plant Genetics and Breeding,
Beijing Agricultural University, China
Positions
2016-present Adjunct Professor, Faculty of Health Sciences,
University of Macau
2021-present Head and Chair Professor, Division of Life Science,
The Hong Kong University of Science and Technology
2009-2021 Professor, Department of Anatomy,
University of Kansas Medical Center
2008-present Investigator, Stowers Institute for Medical Research
2005-2009 Associate professor, Department of Anatomy,
University of Kansas Medical Center
2004-2008 Associate investigator, Stowers Institute for Medical Research
2002-2005 Assistant professor, Department of Anatomy,
University of Kansas Medical Center
2000-2003 Assistant investigator, Stowers Institute for Medical Research
1996-1999 Postdoctoral fellow, Carnegie Institution of Washington/Howard Hughes Medical Institute, Baltimore, Maryland
Representative Publications
  • Lu T, Wang S, Gao Y, Mao Y, Yang Z, Liu L, Song X, Ni J, Xie T. COP9-Hedgehog axis regulates the function of the germline stem cell progeny differentiation niche in the Drosophila Ovary. Development. 2015 Dec 15;142(24):4242-52. doi: 10.1242/dev.124768.
  • Fu Z, Geng C, Wang H, Yang Z, Weng C, Li H, Deng L, Liu L, Liu N, Ni J, Xie T. Twin promotes the maintenance and differentiation of germline stem cell lineage through modulating multiple pathways. Cell Reports. 2015 Nov 17;13(7):1366-79. doi: 10.1016/j.celrep.2015.10.017. Epub 2015 Nov 5.
  • Wang S, Gao Y, Song X, Ma X, Zhu X, Mao Y, Yang Z, Ni J, Li H, Malanowski KE, Anoja P, Park J, Haug J and Xie T. Wnt signaling-mediated redox regulation maintains the germ line stem cell differentiation niche. eLife. 2015; 4:e08174. DOI: 10.7554/eLife.08174.
  • Ouyang J, Yu W, Liu J, Zhang N, Florens L, Chen J, Liu H, Washburn M, Pei D, Xie T. Cyclindependent Kinase-mediated Sox2 Phosphorylation Enhances the Ability of Sox2 to Establish the Pluripotent State. J Biol Chem. 2015; 290(37):22782-94.
  • Pan L, Wang S, Lu T, Weng C, Song X, Park JK, Sun J, Yang ZH, Yu J, Tang H, McKearin DM, Chamovitz DA, Ni J, Xie T. Protein competition switches the function of COP9 from self-renewal to differentiation. Nature. 2014; 514(7521):233-6.
  • Yan D, Neumüller RA, Buckner M, Ayers K, Li H, Hu Y, Yang-Zhou D, Pan L, Wang X, Kelley C, Vinayagam A, Binari R, Randklev S, Perkins LA, Xie T, Cooley L, Perrimon N. A regulatory network of Drosophila germline stem cell self-renewal. Dev Cell. 2014; 28(4):459-73.
  • Ma X, Wang S, Do T, Song X, Inaba M, Nishimoto Y, Liu LP, Gao Y, Mao Y, Li H, McDowell W, Park J, Malanowski K, Peak A, Perera A, Li H, Gaudenz K, Haug J, Yamashita Y, Lin H, Ni JQ, Xie T. Piwi is required in multiple cell types to control germline stem cell lineage development in the Drosophila ovary. PLoS One. 2014; 9(3):e90267.
  • Wang Y, Xie T. Extracellular, stem cells and regenerative ophthalmology. J Glaucoma. 2014; 23(8 Suppl 1):S30-3.
  • Chen S, Li H, Gaudenz K, Paulson A, Guo F, Trimble R, Peak A, Seidel C, Deng C, Furuta Y, Xie T. Defective FGF signaling causes coloboma formation and disrupts retinal neurogenesis. Cell Res. 2013; 23(2):254-73. (advance online publication 13 November 2012; doi:10.1038/cr.2012.150).
  • Chen S, Lewallen M, Xie T. Adhesion in the stem cell niche: biological roles and regulation. Development. 2013; 140(2):255-65. (doi:10.1242/dev.083139).
Fellowships and Academic Honors
2003 M. R. and Evelyn Hudson Foundation prize
1992-1996 Busch Predoctoral Fellowship, Rutgers University, USA
1984-1987 Highest Academic Honor, Beijing Agricultural University, China
Professional Affiliation
  • The Genetics Society of America
  • The Society of Developmental Biology
  • The International Society for Stem Cell Research
  • The Association for Research in Vision and Ophthalmology
Editor and Editorial Board Member
2013-present The advisory board member of Development
2012-present Associate Editor of Translation Vision Science and Technology
2012-present The advisory board member of Biology Open
2011-present Editorial board member of Cell & Biosciences
2009-present Editorial board member of Journal of Molecular and Cellular Biology
2008-present Editorial board member of Stem Cell Review and Reports
2006-present Editorial board member of Cell Research
2004-present Editorial board member of Developmental Dynamics