Talk title Computational biology studies, at the heart of cardiovascular precision medicine
Speaker Dr. Ning-Yi SHAO
Postdoctoral Fellow
Cardiovascular Institute
Stanford University
Date & Time 10 September 2018 (Monday) 10:30-11:30
Venue Room G004, E12 Building (University of Macau)
Abstract Heart disease is the top adult killer in the Western world and bringing a considerable health burden to the society and individuals. Recently with the application of next generation sequencing (NGS), the bottleneck of the biomedical studies transferred from data generation to data analysis.
Effectively integrating large-scale data analysis with “wet” biology is the essential way to investigate the whole system. In this talk, I will introduce my studies about the cis-regulation mechanisms of heart
development and reprogramming using multi-omics integration methods, including the molecular mechanisms of human heart development, and the efficiency of extrapolation of mouse model to
human during cardiac differentiation. Further, I will talk about the multi-omics application in the human disease to find the missing link of genotypes to phenotypes.